All About HIPEC Treatment

The HIPEC surgery in Indiais performed with cytoreductive surgery, this approach widens the range of health benefits for the patient. The response of HIPEC treatment is even better than other alternatives for treating peritoneal mesothelioma. Here, we will know about how HIPEC treatment with cytoreductive surgery is merited over the Whipple procedure, trisegmental surgery, esophagectomy, and right lobe hepatectomy.

  • Infections

It has been concluded that patients operated with HIPEC surgery showcase a lower risk rate of infection. Mere 5.4 % of patients experience superficial infections post-HIPEC treatment. The infection rate of deeply embedded incision infection is even less than the superficial infections at 1.7%.

  • Mortality

When compared with other alternative procedures for treating peritoneal mesothelioma namely, Whipple procedure, trisegmental surgeries, esophagectomy, and right lobe hepatectomies, HIPEC treatment showed a considerably better mortality rate. With 30-day mortality rate, HIPEC treatment is comparatively safer than above mentioned alternate options.

  • Organ space infections

Out of Whipple procedure, trisegmental surgeries, right lobe hepatectomies, and HIPEC treatment, HIPEC treatment reports 7.2% rate of organ space infections which is the least of all.

  • Revision surgery

Th clear win of HIPEC treatment in respect of the rate of revision surgery is when compared with esophagectomy. While HIPEC treatment results into only 6.8% of its patients to be treated with revision surgery, patients operated with esophagectomy show a rate of 14.4%. 

  • Stay at the hospital

The recovery period after HIPEC treatment can last up to three months but the stay at hospital post-treatment is almost in a week. On the other hand, patients treated with either the Whipple procedure or esophagectomy are associated with a comparatively higher number of days for hospital stay.


Procedure of HIPEC treatment

  1. Cytoreductive surgery with HIPEC (hyperthermic intraperitoneal chemotherapy)

It is done to remove the maximum safe level of tumors in the abdomen, it is important for enhancing the safety of the treatment. The HIPEC treatment centers in India recommend it also for curbing the chances of recurrence of cancer. For this, heated chemotherapy is used to bathing the abdomen. Throughout HIPEC, the temperature is maintained at 104 F. With the help of an efficient perfusion system, chemotherapy drugs are pumped in and outside of the patient. In this step, the cancerous cells are potentially eliminated. Cleaning of the abdominal cavity with a saline solution is significant to end the procedure safely.

  • Early postoperative intraperitoneal chemotherapy

All experienced and scientifically progressed HIPEC treatment centers in India follow this step, it is based on Dr. Sugarbaker’swork. He suggested use of paclitaxel as the chemotherapy drug because it has high molecular weight. Spread over a span of five days, early postoperative intraperitoneal chemotherapy is administered with ‘non-heated intraperitoneal chemotherapy’. This step enhances the detail-intensive removal of the deeply embedded cancerous cells. In addition, treating debilitating fluid build-up or ascites are also effectively done by this.

  • Normothermic intraperitoneal chemotherapy (NIPEC)

Adjuvant chemotherapy procedures provided either through intraperitoneal paclitaxel only or intraperitoneal pemetrexed plus intravenous (IV) cisplatin are parts of this last step pf Dr. Sugarbaker’s work.

Recovery after HIPEC treatment

On average, a normal HIPEC treatment can last anywhere between six to eighteen hours. Considering the detailed procedure of HIPEC treatment, the time taken for completing it is not extensive. But the recovery after the complete HIPEC treatment can take up to three months. The health of the patient during this time should progress positively. The HIPEC specialists in Delhirecommend a close adherence to the prescribed practices of the rehabilitation program for effective recovery.

Risks of HIPEC treatment

Strict follow-up with the standard procedure of HIPEC cancer treatment is significant to minimize the risks of side-effects and complications. The risks associated with HIPEC can become severe which can deteriorate the condition of the patient to serious decrement in their health. The below-mentioned risks can develop due to HIPEC surgery:

  • Bleeding
  • Blood clots
  • Bowel obstruction
  • Fistula
  • Infection
  • Loss of appetite
  • Myelosuppression
  • Pneumonia
  • Sepsis
  • Urinary tract infections

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