What are Genetic Liver Diseases?

liver diseases treatment at Cusp Surgeon

Chronic liver diseases may be caused due to genetic defects or other metabolic issues. The most common inherited liver diseases are hemochromatosis and alpha-1 antitrypsin deficiency. Most of these diseases occur due to the problem in metabolic enzymes.


Hemochromatosis is a disease in which residues of iron is gathered in the liver and other organs. Though there is another kind of hemochromatosis which occurs due to thalassemia or due to constant alcohol drinking in the long term. However, talking about genetic hemochromatosis is most common especially in the USA where one out of a 200th person is a victim of this disease. since it is a genital disease if any of the one family members are suspected of this form of a disease then, parent, siblings and other relatives and family members are also at risk of having the same. Moreover, studies reveal that this form of the disease is more common in men than women as women do not show indications of iron overload at least till menopause, and another factor is a loss of blood during menstruation.

Doctors engaged in genetic liver diseases treatment in Delhi found few common symptoms regarding  people suffering from hemochromatosis :

•             If a person is already affected by liver disease

•             Pain in joints

•             Feeling of fatigue

•             Uncertain weight gain

•             Skin bronzing or darkening of the skin

•             Abdominal pain

•             Loss of sexual desire

 Moreover, doctors performing liver disease treatment in South Delhi, exert that a person suffering from hemochromatosis may further develop a risk of other diseases such as- diabetes and heart disease and may also develop liver cancer, cirrhosis, testicular atrophy, and infertility.

In case hemochromatosis is a diagnosedwhena person is ordered to take a blood test to know if any surplus iron is found in the blood. Doctors may ask for a liver biopsy also. If excess iron is detected then the doctor will have to perform phlebotomy. It is a procedure to remove all the surplus iron from the blood. In this procedure, one- halfliter of blood is removed from your body on a weekly basis as per the condition of the patient until and unless it stops making iron. Moreover, as it maximizes the risk of other diseases, therefore, doctors performing treatment for liver cancer treatment in Delhi, strictly recommend you to come for periodic screening to detect liver cancer.

Alpha-1 Antitrypsin Deficiency

In Alpha -1 Antitrypsin deficiency as the name suggests it either lacks or produces this important protein known as alpha-1 antitrypsin below normal levels. However, people experiencing alpha-1 antitrypsin deficiency are able to produce this protein by itself and this disease is usually surrounded in the liver and thus,  it doesn’t enter the bloodstream. In addition to it, doctors of liver damage treatment in Delhi also explains the possibilities that people suffering from this disease may also encounter lungs damage due to low levels or in other cases non-presence of these vital proteins. Moreover, people might develop a risk of cirrhosis also.

Some commonly found symptoms of this disease are:-

  • Shortness of breath leading to. Lungs damage
  • Nausea
  • Swelling in ankles and feet
  • Uncertain weight gain
  • Change in the shape of the chest
  • Feeling fatigued
  • Persistent cough

Although, there is no specific treatment for alpha-1 anti-trypsin however it can be treated by replacing the protein content in the bloodstream.

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